Modelling Huntington's and Parkinson's diseases using dynamic state feedback
A. Lõrincz
Sixth Annual Computational Neuroscience Meeting, Montana, U.S.A.
Collection of abstracts p. 97
(July 6-10, 1997)
Abstract
The speed field tracking based Static and Dynamic State Feedback control
scheme that utilizes the estimate of the inverse dynamics and is capable
of controlling overcontrolled plants of arbitrary order is suggested as the
functional model of the basal ganglia - thalamocortical loops owing to
the similarities between the two constructs including the organization of
the SDS scheme into parallel channels and the classification of
preparatory and motion related neurons. Consequences on Huntington's
and Parkinson's diseases are described. It is suggested that cooling the
subthalamic nucleus may restore normal movement speed in Parkinsonian
subjects.
